SM1 10mg – Research Peptide Overview
SM1 10mg is a synthetic analogue of human glucagon-like peptide-1 (GLP-1), sharing approximately 94% sequence homology with the native hormone. It incorporates a C18 fatty diacid modification that enables strong albumin binding, extending its half-life significantly compared to native GLP-1. SM1 is among the most widely studied GLP-1 receptor agonist compounds in biochemical research, used to investigate incretin signalling and glucose homeostasis pathways. SM1 10mg is supplied as a lyophilised powder in a sealed research vial. For laboratory and research use only, not for human or veterinary use.
Pyrox Labs sources SM1 10mg exclusively from vetted manufacturing partners, with independent batch testing carried out by Janoshik Analytical. This 10mg format is intended for researchers requiring a higher-strength reference standard compared with our 5mg vials, particularly where larger-scale experimental protocols call for extended supply per batch. Researchers new to this compound family can review our dedicated SM1 Research Guide or broader GLP-1 Research Compounds UK overview.
Contents

Product Details
| Compound | SM1 |
| Quantity | 10mg |
| Form | Lyophilised powder |
| Batch | OZ100526 – view Certificate of Analysis |
| Purity | Research grade, independently verified |
| Packaging | Sterile sealed glass vial |
| Use | Laboratory research use only |
Research & Handling
- Supplied strictly for laboratory research use only
- Suitable for controlled experimental environments
- Handled using standard laboratory safety procedures
- Review COA and batch data before use
- Not for human consumption or medical application
SM1 is frequently referenced in scientific literature relating to GLP-1 receptor pathway research and metabolic signalling studies. Researchers wanting further scientific context can review published literature via a PubMed search for semaglutide and GLP-1 receptor research.
Research Applications
Within laboratory settings, SM1 10mg is primarily investigated for its role as a GLP-1 receptor agonist, with research interest centred on incretin-mediated insulin secretion, gastric emptying rate, and appetite-regulation pathways in model systems.
Its extended half-life, a result of the C18 fatty diacid side chain enabling reversible albumin binding, makes it a useful reference compound when researchers are comparing pharmacokinetic profiles against shorter-acting GLP-1 analogues.
Ongoing peptide research also explores downstream signalling cascades linked to glucose homeostasis, offering researchers a well-characterised compound with an established body of published data to reference alongside their own findings. Researchers comparing SM1 10mg against other GLP-1 analogues in our range can browse our full GLP-1 Research Compounds category.
As with all compounds supplied by Pyrox Labs, SM1 10mg is intended solely to support this kind of controlled, laboratory-based investigation. Reconstitution is typically carried out using Bacteriostatic Water 3ml or Bacteriostatic Water 10ml, drawn with a Reconstitution Syringe 5ml 21G. For step-by-step guidance, see our How to Reconstitute Peptides guide.
Storage Guidance
- Store lyophilised powder in a freezer (-20°C) for long-term storage, or refrigerated (2–8°C) for short-term use, away from light
- Once reconstituted, store refrigerated (2–8°C) and use within the timeframe indicated by your research protocol
- Do not freeze reconstituted solution
- Avoid repeated freeze-thaw cycles
Frequently Asked Questions
Is SM1 10mg legal in the UK?
Yes, when supplied and used strictly for laboratory research purposes. SM1 10mg is not supplied for human use, medical use, or therapeutic application.
Does SM1 10mg have a Certificate of Analysis?
Tested batches are independently verified for purity and identity – check the batch code on your vial against our CoA Hub. View the verified Certificate of Analysis for this batch, or search by product name and batch/lot number on our COA Hub.
How is SM1 10mg supplied?
Each vial in lyophilised powder form, supplied in a sterile sealed glass vial.
How fast is UK delivery?
Orders placed before 4:30pm are dispatched the same working day, Monday to Friday, with tracked delivery. Orders after that go the next working day.
Who performs third-party testing on SM1 10mg?
All Pyrox Labs compounds are independently verified by Janoshik Analytical, a specialist third-party laboratory used widely across the research compound industry.
Can SM1 10mg be reconstituted for research use?
Yes, researchers typically reconstitute the lyophilised powder using bacteriostatic water as part of their own experimental protocol. Pyrox Labs does not provide dosing or administration guidance, as this product is not intended for human or animal use.
How does SM1 10mg differ from the 5mg option?
It offers a higher-strength reference standard than our 5mg vials, giving researchers more extended supply per batch for larger-scale or longer-running experimental protocols.
Delivery Information
- Same-day dispatch on orders placed before 4:30pm, Monday to Friday (otherwise next working day)
- Free Royal Mail Tracked 24 on all UK orders over £50
- Royal Mail Tracked 24 available for £5.00 on UK orders under £50
- Royal Mail Tracked 48 available for £4.00 on UK orders under £50
- All orders sent in discreet, plain packaging with no external branding
- Tracking details are emailed once your order has been dispatched







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